Lund University

Reconstructing the brain: approaches to treating Parkinson’s disease

Dr Malin Parmar and colleagues concisely describe in an ACNR review efforts over the past 30 years to develop a treatment for Parkinson’s disease patients that replaces destroyed nerve cells in the brain. Many different approaches are being taken, from brain cell transplants to using pluripotent stem cells. Now, a technology called ‘direct neural conversion’ can be added to the arsenal of tools researchers are using.

Stem cell transplants for Parkinson’s disease edging closer

A major breakthrough in the development of stem cell-derived brain cells has put researchers on a firm path towards the first ever stem cell transplantations in people with Parkinson’s disease. A new study presents the next generation of transplantable dopamine neurons produced from stem cells. These cells carry the same properties as the dopamine neurons found in the human brain.

Interview with Malin Parmar: cell therapy for Parkinson’s disease

Malin Parmar heads a research group focused on developmental and regenerative neurobiology at Lund University in Sweden. The ultimate goal of her research is to develop cell therapy for Parkinson’s disease.

At this year’s Hydra summer school I spoke to Malin about how she got started in stem cell research, what she’s working on at the moment, and her view of the prospects for treating Parkinson’s disease with stem cells.

Research from our partners: ethical issues, stem cell research and gastroenterology

In “Human stem-cell research in gastroenterology: experimental treatment, tourism and biobanking”, EuroStemCell ethics expert and Professor Emeritus of Lund University’s Department of Medical Ethics Göran Hermerén outlines some of the prospects for applying stem cell therapies to gastroenterological diseases, and related ethical issues.

NeuroStemcell group finds a new way to turn stem cells into neurons

A study coordinated by Malin Parmar at the University of Lund has developed  a new method to convert human embryonic stem cells (ESCs) into functioning brain cells. Researchers say that the technique is twice as fast to perform as previous methods and reduces the risk of tumour formation, one of the most common obstacles in stem cell transplantations.

Parkinson’s disease: how could stem cells help?

Last updated:
12 Dec 2014

Parkinson's disease affects millions of people worldwide. Although the symptoms can be treated, there is no known cure. Scientists are investigating how regenerative medicine and stem cell science could be used to treat or prevent the disease.

Ethics and reprogramming: ethical questions after the discovery of iPS cells

Last updated:
5 Nov 2015

Reprogramming allows us to turn any cell of the body into a stem cell. This discovery surprised many scientists and changed the way they think about how cells develop. Does the new technology also change ethical discussions about stem cell research? What new questions does it raise?

Origins, ethics and embryos: the sources of human embryonic stem cells

Last updated:
5 Nov 2015

Where do researchers get embryonic stem cells? This is the question that gives rise to much of the controversy surrounding human stem cell research. Should scientists limit themselves to using embryos left over from fertility treatment? Why not create embryos especially for research and maximize our chances of success?

Stem cell patents: ethical aspects

Patent law addresses a problem that is basically ethical: what is a fair balance between the interests of the inventor, the industry, potential users and society at large? 

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