Stem Cell Biology
Are you the talented PhD student who will develop new stem cell-based models of inherited heart diseases? You would be part of a team in the Department of Anatomy & Embryology that aims to use cardiomyocytes derived from human pluripotent stem cells (hPSCs) to detect changes caused by genetic mutations . Your studies would involve using cell culture, advanced genetic engineering techniques and microscopic imaging, as well as other electrophysiological methods to tackle this challenge.
Stem Cell Biology
Stem cells are defined by the dual capacity to self-renew and to differentiate. These properties sustain homeostatic cell turnover in adult tissues and enable repair and regeneration throughout the lifetime of the organism. In contrast, pluripotent stem cells are generated in the laboratory from early embryos or by molecular reprogramming. They have the capacity to make any somatic cell type, including tissue stem cells.
Applications are invited for a four-year PhD studentship at University College London (UCL, London, United Kingdom) to work on an exciting translational research project aimed at developing a new strategy for ex vivo gene therapy of Duchenne muscular dystrophy (DMD)  based upon the combination of Human Artificial Chromosomes  and induced Pluripotent Stem (iPS) Cells . This post will be based in the laboratory of Dr Francesco Saverio Tedesco , UCL Research Department of Cell and Developmental Biology, Division of Biosciences.
The position is embedded in a Collaborative Research Project OTOSTEM (EC-FP7-Health-project No. 603029) that represents a EU-US network of nine research groups working in the area of neurosensory stem cell biology and regenerative therapy of the inner ear (for further details see www.otostem.org). The position requires a recent Master or Diploma degree in biology, biochemistry, chemistry, medicine, pharmacy or similar scientific discipline.
Vacancy: CognitionNet FP7-PEOPLE-2013-ITN-607508
Application Code: CESR5
Epigenetic regulation of MeCP2 using IPSC-derived neural cells generated from patients with Rett syndrome
One ESR Marie Curie training position is available at the Center for Neurogenomics and Cognitive research (www.cncr.nl) VU University Amsterdam in the teams of Danielle Posthuma, Sophie van der Sluis, and Vivi Heine, within the Innovative Doctorate Program CognitionNet.
Primary Supervisor: Dr. Brian Hendrich, Cambridge Stem Cell Institute
Microsoft Research Supervisor: Prof. Stephen Emmott