Research:

The laboratory of Stem Cell Epigenetics, headed by Giuseppe Testa and associate member of the EuroSyStem European Research Consortium, invites applications for a postdoctoral position to study the role of histone lysine methylation and demethylation in the physiology of neural differentiation and its derangement in gliomagenesis. The focus of the lab is on the epigenetic mechanisms that enable the establishment and maintenance of lineage choices and that underlie lineage aberrations in cancer. We use mice and mouse embryonic stem cells as model systems to study the physiology of neural differentiation and its aberrations during gliomagenesis. The successful candidate will characterize the function of histone methyltransferases and demethylases using innovative mouse models that were recently established in the lab.

The position offers a competitive salary and the benefits of the International Postdoc Program (SIPOD) at the IFOM-IEO-Campus.

Requirements:

MD or PhD in Molecular Biology, Genetics or Biochemistry with a solid background in the analysis of gene expression. Expertise in neurobiology or tumor biology is highly desirable. We are looking for a highly motivated scientist who wishes to join an interactive team at the cutting egde of research in histone methylation and mouse genetics (Natoli et al. Curr. Opin. Drug Discov. Develop. 2009; De Santa et al. EMBO J. 2009; Burgold et al. PLoS One 2008; De Santa et al. Cell 2007; Testa et al. Nature Biotechnology 2003).

How to apply:

For inquiries please contact Giuseppe Testa at

giuseppe.testa@ifom-ieo-campus.it

http://www.ifom-ieo-campus.it/research/testa.php