iPS

Komórki macierzyste – nasza przyszłość: wprowadzenie do tematyki indukowanych pluripotencjalnych komórek macierzystych [video]

Last updated:
26 Nov 2012

W tym przykuwającym uwagę szesnastominutowym filmie wiodący naukowcy opowiadają historię indukowanych pluripotencjalnych komórek macierzystych (komórek iPS). To niezwykłe odkrycie naukowe zmieniło całkowicie sposób myślenia o biologii człowieka. Za to odkrycie Shinya Yamanaka wraz z Johnem Gurdonem zostali uhonorowani nagrodą Nobla w dziedzinie medycyny w 2012 roku.

Renowned experts offer advice on generating human induced pluripotent stem cell banks

Procedures for production of induced pluripotent stem (iPS) cells for use in therapy are reaching the point at which they will be suitable for use in clinical trials.
 
A team of internationally renowned scientists led by the MRC Centre for Regenerative Medicine’s Emeritus Professor Sir Ian Wilmut have today published an opinion piece in the journal CellStemCell, arguing that while in the future it might be possible to derive iPS cell lines on an individual basis – so that a patient would receive his or her own cells as a treatment – it seems unlikely that these will be used as a source for large numbers of patients in the near future due to time and cost restraints.

Cellule souches - le futur: une introduction aux cellules iPS [video]

Last updated:
26 Nov 2012

Dans cette vidéo fascinante de 16 minutes, d'éminents scientifiques racontent l'histoire des cellules souches pluripotentes induites (cellules iPS).
Cette découverte scientifique extraordinaire a changé notre perception de la biologie humaine et résultat à l'attribution du prix Nobel de médecine pour Shinya Yamanaka et John Gurdon, en 2012.

Scottish Stem Cell Stories: A graphic short story of stem cell research

Last updated:
26 Sep 2013

Making blood from stem cells, iPS cells from skin cells and improving the lives of those with diabetes are just a few of the stories that are touched on in this delightful comic. A colourful and enticing introduction to some of the stem cell research happening in Scotland and the directions the science is taking. Ideal for use in the classroom, at festivals and events.

Animation: Disease modelling with cells

How are stem cells used to model disease in the laboratory? This 3-minute animation gives a clear, simple and visually appealing explanation of what disease modelling is, why it is useful and how it is done.

This animation was created for EuroStemCell by animator Duncan Brown, with scientific content by researcher Dr Christian Unger and voiceover by Dr Nathan Adams. It is supported by an accompanying factsheet on reprogrammed cells in disease modelling.

Reprogramming cells: new research reveals a detour on the path to iPS cells

Reprogramming allows us to turn any cell of the body into a stem cell. Since its discovery in 2006 the technique has become widely used in labs around the world. But the process is inefficient and many questions remain about how reprogramming works. PhD student James O'Malley is studying some of these challenging issues. Here he talks about his latest findings, which were published in the journal Nature on 2 June 2013.

Etyka i przeprogramowanie: pytania natury etycznej po odkryciu komórek iPS

Last updated:
26 Nov 2012

Przeprogramowanie pozwala nam zmienić dowolną komórkę ciała w komórkę macierzystą. To odkrycie zaskoczyło wielu naukowców i zmieniło ich sposób postrzegania rozwoju komórek macierzystych. Czy nowa technologia zmienia również dyskusję etyczną dotyczącą badań nad komórkami macierzystymi? Jakie nowe pytania powstają?

Ethik und Reprogrammierung: ethische Fragen nach der Entdeckung von iPS Zellen

Last updated:
26 Nov 2012

Die Reprogrammierung ermöglicht es jede beliebige Zelle des Körpers in eine Stammzelle umzuwandeln. Diese Entdeckung war für viele Wissenschaftler überraschend und veränderte ihre Denkweise darüber, wie sich Zellen entwickeln. Verändert diese neue Technologie auch die ethischen Diskussionen zur Stammzellforschung? Welche neuen Fragen bringt sie mit sich? 

New tools for disease research: reprogrammed cells in disease modelling

Last updated:
15 Jul 2013

We need research to understand and fight disease. But research is often limited by access to patients and availability of diseased tissues to study. 'Disease models' can help overcome these problems by enabling scientists to examine diseases in the lab. Stem cells, including reprogrammed or 'iPS' cells, are a new source of cells that can be used as models for diseases which are otherwise difficult to explore.

Folge 111: iPS-Zellen

How are iPS cells created in the laboratory? Short film in German.

Für die bahnbrechende Entwicklung von induzierten pluripotenten Stammzellen wurde 2012 der Medizin-Nobelpreis vergeben. Wie genau iPS-Zellen im Labor entstehen, erklärt Jan Wolkenhauer in der 111. Folge der Kreidezeit.

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