While blood stem cells have been used clinically for over 40 years, it was the discovery of human embryonic stem cells in 1998, that has built expectations for people affected by a multitude of degenerative, chronic and fatal diseases with no cures or effective treatments. The speed with which therapies were expected to roll out of the lab did not take into consideration the complete lack of infrastructure required to make it happen, for many turning potential into frustration.
research
Neue Hilfsmittel zur Erforschung von Krankheiten: Umprogrammierte Zellen zur Modellierung von Krankheiten
Last updated:
15 Jul 2013
Managing the potential and pitfalls of emerging stem cell therapies
Nuovi strumenti per la ricerca medica: Cellule riprogrammate come modello di patologie
Last updated:
15 Jul 2013
MERLIN
Mon, 15/12/2014 - 7:28am — admin
MEsenchymal stem cells to Reduce Liver INflammation (MERLIN) is a four year project that will bring leading European researchers in stem cells and liver disease together with global industrial partners to look at new ways to treat liver disease with stem cells. MERLIN will specifically focus on primary sclerosing cholangitis (PSC), an inflammatory liver disease currently without effective treatments, but will also generate new knowledge that is more widely applicable to stem cell therapy in general.
Study reveals the genesis of brain cells that degenerate in Huntington’s disease
Fri, 21/11/2014 - 9:10am — admin
Elena Cattaneo reports on recent research that examines how a particular type of cell develops in the human brain, and how studies like this fit into the overall picture of research collaboration and funding, in Italy and in Europe.
It took 4 years of continuous experiments of 17 researchers from 6 groups in 2 European countries to understand more about how cells develop in the striatum. The striatum is the area of the brain that degenerates in Huntington’s disease (HD) – a neurological disorder that as of today, has no cure. This work, led by my group at the University of Milan, was published in Nature Neuroscience on 10 Nov 2014.
Making insulin producing beta cells from stem cells – how close are we?
The unseen world: Insulin-producing cells made from human embryonic stem cells
Two recent studies have revealed for the first time how to to generate insulin producing cells, that resemble normal beta cells, in the lab from human pluripotent stem cells. This provides a step forward for a potential cell therapy treatment for diabetes. But how alike are these cells to the beta cells found in our bodies? How close are we to testing these cells in diabetics? And what other questions still remain? In this commentary, Henrik Semb tackles these questions providing perspective in this complex and challenging field.
Investigación y terapia con células madre: tipos de células madre y sus aplicaciones actuales
Last updated:
17 Aug 2012
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This project has received funding from the European Union’s Seventh Framework Programme for research, technological development and demonstration under grant agreement no 241878
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