Portal europeo sobre células madre

Estamos aquí para ayudar a los ciudadanos europeos a entender qué son las células madre.  Ofrecemos información fiable y independiente y probados recursos educativos sobre las células madre y su impacto en la sociedad. Estamos financiados por la Comisión Europea.

Featured stem cell fact sheets, news and resources

Yoshiki Sasai (1962-2014): an appreciation

Yoshiki Sasai was a visionary scientist who pioneered research at the interface between developmental biology and stem cell biology, contributing major discoveries to both fields and sowing the seeds for applications in regenerative medicine.

Stem cells and sports medicine: an overview

Regenerative medicine and stem cell therapies hold much promise for the treatment of various injuries and diseases suffered by sportspeople. While there are currently no approved stem cell treatments, researchers are working on harnessing the process by which stem cells repair and replace damaged tissues and cells.

Challenging an old dogma

Challenging an old dogma

Science teachers usually say that science progresses by challenging old dogmas. In the stem cell field, there is a dogma saying that some blood stem cells in the bone marrow stay quiescent (do not divide) for long periods of time. This way, they avoid DNA damage and malignant mutations that could arise during DNA replication that happens during cell division.

New study raises doubts over the benefits of heart stem cell therapy

Summary

Numerous clinical trials have attempted to test the benefits of using a patient’s own stem cells (taken from the bone marrow) to treat heart disease. Results have been conflicting; some claim significant improvements in heart function, whilst others report none at all. A group at Imperial College London investigated the possible reasons for this inconsistency and found strange, unexplained discrepancies within reports of many of the clinical trials. They have identified a link between claimed success rates and discrepancies, casting doubts over the validity of this treatment.

- 133 reports of 49 clinical trials were investigated
- 600+ discrepancies were found
- Discrepancies ranged from minor to serious mistakes and misrepresentation of data
- Reports with the most discrepancies claimed most benefit to patients, while those without discrepancies showed no improvement in patients’ conditions 

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