A team of Yale researchers has discovered that infection by the Zika virus (ZIKV) stops neural stem cells dividing in the developing human brain, thereby causing the birth defect microcephaly. The ZIKV does this by diverting a key protein necessary for neural stem cell division. The researchers also reported that antiviral nucleoside analogs, including the FDA-approved drug Sofosbuvir (normally used to treat Hepatitis C virus infection), inhibit ZIKV replication and protect human neural stem cell from death.
The development of new precise and fast genome editing tools, like CRISPR/Cas9, has changed the landscape of biomedical research forever. Much has been written about the technology, but what does it mean for the field of stem cell research and regenerative medicine? Take an in-depth look at genome editing and stem cells with our Questions and Answers.
Part of the fascinating potential of stem cells is their ability to provide replacement cells and tissues to treat diseases. In order to do this most effectively, scientists need to be able to create differentiated cells quickly and accurately.
Díky Masarykově univerzitě, která je partnerem projektu EuroStemCell pro Českou republiku, s potěšením poskytujeme některé z našich nejpopulárnějších informačních textů v češtině.
Thanks to Masaryk University, EuroStemCell’s partner in the Czech Republic, we are pleased to provide some of our most popular fact sheets in Czech.
From the moment we began to unlock the secrets of the genome, the complete set of DNA including all genes and understand the effects that genes can have on human health, the idea of modifying the human genome – and hence controlling these effects – has held both promise and peril. Visions of a bright future free from the sufferings of genetic disease contrast starkly with darker fears of a genetically-engineered ‘Brave New World’.